Mixing COVID-19 vaccine doses leads to more reactions, study finds, which may be 'first sign of success'
An 830-participant trial in the UK that looked at mixing and matching COVID-19 vaccines has produced preliminary evidence that people who mix different vaccines are more likely to experience mild or moderate symptoms such as chills, fatigue and fever. The trial saw participants administered two doses of AstraZeneca, two doses of Pfizer or one of each. While the side effects were short lasting, they are the first suggestion that mixing vaccines could produce a stronger immune response. Data on effectiveness is not yet available.
Published: May 12, 2021
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